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許惠恒主任

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許惠恒醫師
 

現職︰
1. 台中榮民總醫院院長
2. 國立陽明大學兼任教授、國防醫學院兼任教授、國立中興大學生命科學院合聘教授、中山醫學大學醫學系兼任教授
3. 中華民國糖尿病衛教學會常務監事
4. 中華民國糖尿病學會常務理事
5. 中華醫學雜誌編輯委員
6. Diabetes Research and Clinical Practice 副主編 (Associate Editor)
7. 世界糖尿病聯盟 (International Diabetes Federation, IDF) 西太平洋區
    (Western Pacific Region) 主席 (President elect 2013-2015, President 2016-2017)
學歷︰
1. 國防醫學院醫學士 (1976-1983)
2. 國防醫學院醫學科學研究所博士 (1985-1989)
3. 台灣大學醫務管理研究所碩士 (2001-2003)
經歷︰
1. 三軍總醫院內科住院醫師、總醫師 (1983-1990)
2. 三軍總醫院新陳代謝科主治醫師 (1990-1996)
3. 台中榮民總醫院新陳代謝科主任 (1996-2000)
4. 台中榮民總醫院教學研究部主任 (2000-2005)
5. 美國史丹福大學醫學院臨床研究中心 Clinical Research Fellow
獲獎事蹟或殊榮︰
1. 2011 國防醫學院傑出校友獎
2. 2006-2011 糖尿病衛教學會理事長
3. 2010 內科醫學會內科雜誌綜論類論文首獎
4. 2009 起擔任IDF期刊副主編Associate Editor of Diab Res Clin Pract
5. 2008 內科醫學會內科雜誌綜論類論文首獎
6. 2007 糖尿病學會默沙東優秀論文獎
7. 2006 糖尿病學會陳芳武教授傑出研究獎
8. 1998 糖尿病會諾和諾德學術獎
9. 1996 營養學會陳尚球教授學術論文獎
教職︰教育部部定教授 (陽明大學、中興大學生醫所、中山醫學大學醫學系兼任教授)
專科證書︰
1. 內科專科醫師證書
2. 內分泌暨新陳代謝科專科醫師證書
3. 老年醫學會專科醫師證書
4. 肥胖醫學會專科醫師證書
5. 衛教師證書
參加學會︰
1. 內科醫學會
2. 中華民國糖尿病學會
3. 台灣糖尿病衛教學會
4. 台灣老年醫學會
5. 肥胖醫學會
專科學會︰
1. 中華民國內科學會
2. 中華民國內分泌學會
3. 中華民國糖尿病學會
4. 中華民國糖尿病衛教學會
專長︰糖尿病、高血脂症
研究興趣︰糖尿病、高血脂症、血管硬化之研究
進行中計劃︰
1. 體重變化時脂肪組織中吞噬細胞之功能特性與胰島素阻抗之關連. NSC98-2314-B-075A-002-MY3 總執行期限:98/08/01-101/07/31(新制多年期)   (國科會三年期計劃)
2. 白藜蘆醇對吞噬細胞反向膽固醇轉送及細胞凋零之影響:mTOR角色探討. TCVGH-1013001C 執行期限:101/01/01-101/12/31   (院內計劃)
3. 服用抗糖尿病藥物過氧化體增殖劑活化器r與糖尿病病人血清HMGB1蛋白關聯性之探討. TCVGH-1013002D 執行期限:101/01/01-101/12/31   (院內計劃)
4. MicroRNA-33在糖尿病合併血脂異常及心臟血管疾病的角色研究. TCVGH-YM1000102 執行期限:100/01/01-101/07/31  (院校合作─榮陽計劃)
著作 (Corresponding*)︰
1. Chao YC, Fuh M MT, Shian LR, Jeng CY, SHEU HH: The effects of various fruits on serum glucose and insulin kinetics in diabetes.   Medical Science (3):243-247, 1986.
2. SHEU WHH, Sheen TY, Chang FY, Chen TC, Cheng CY, Tu YC: Pseudomyxoma Peritonei ----- Four cases reports. Chinese J of Gastroenterology 3:143-147, 1986.
3. Shen DC, Davison MB, Kuo SW, SHEU WHH: Peripheral and hepatic insulin antagonism in hyperthyroidism. J Clin Endocrinol and Metab 66(3):565-569, 1988.
4. Swislocki ALM, Hoffman BB, SHEU W HH, Chen YDI, Reaven GM: Effect of prazosin treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. Am J Med 86 (suppl. 1B):14-18, 1989.
5. SHEU WHH, DMSc. Thesis: Evaluation of insulin resistance and high density lipoprotein turnover in patients with hypertension. Institute of Medical Sciences, Graduate School of National Defense Medical Center, Taipei, Taiwan, ROC. June, 1989.
6. SHEU WHH, Hollenbeck CB, Wu MS, Jaspan JB, Chen YDI, Reaven GM: Effect of difference in glucose infusion rate on quantification of hepatic glucose production. J Clin Endocrinol and Metab 70:1354-1360, 1990.
7. Fuh M MT, SHEU WHH, Shen D C, Wu DA, Chen YDI, Reaven GM: Metabolic effects of diuretic and beta-blocker treatment of hypertension in patients with Non-insulin-dependent diabetes mellitus. Am J Hypertens 3:387-390, 1990.
8. Wu MS, Johnston P, SHEU WHH, Hollenbeck CB, Jeng CY, Goldfine ID, Chen YDI, Reaven G.M.: Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients. Diabetes Care 13:1-8, 1990.
9. SHEU WHH, Swisloscki ALM, Hoffman BB, Reaven GM, Chen YDI: Effect of prazosin treatment on HDL kinetics in patients with hypertension. Am J Hypertens 3:761-768, 1990.
10. Johnston PC, Hollenbeck CB, SHEU WHH, Chen YDI, Reaven GM: Acute chagnes in plasma non-esterified fatty acid concentration do not modify hepatic glucose production in people with type II diabetes. Diabetic Medicine 7:871-875, 1990.
11. SHEU WHH, Swislocki ALM, Hoffman BB, Reaven GM: Comparison of the effect of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertenison.   Am J Hypertens 4:199-205, 1991.
12. Chen YDI, SHEU WHH, Swislocki ALM, Reaven GM: High density lipoprotein turnover in patients with hypertension. Hypertension 17:387-393, 1991.
13. SHEU WHH*, Shieh SM, Shen DC, Jeng CY, Fuh M MT, Chen YDI, Reaven GM : Insulin resistance and abnormal electrocardiograms in patients with high blood pressure. Am J Hypertens 5:444-448, 1992.
14. Shieh SM, SHEU WHH, Shen DC, Jeng CY, Jeng JR, Fuh MMT, Chen YDI, Reaven GM : Improvement in metabolic risk factors for coronary heart disease associated with a cilazapril treatment. Am J Hypertens 5:506-510, 1992.
15. Shieh SM, SHEU WHH, Shen DC, Fuh MMT, Chen YDI, Reaven GM : Glucose, insulin and lipid metabolism in doxazosin-treated patients with hypertension. Am J Hypertens 5:827-831, 1992.
16. SHEU WHH*, Jeng CY, Fuh MMT, Hou JJC: Reproducibility of insulin sensitivity measured by modified insulin suppression test. J Formosan Med Assoc 91:859-863, 1992.
17. Reaven GM, Chen YDI, Hollenbeck CB, SHEU WHH, Ostrega D, Polonsky KS.: Plasma insulin, C-peptide and proinsulin concentrations in obese and non-obese individuals with varying degrees of glucose tolerance.  J Clin Endocrinol Metab 76:44-48, 1993.
18. SHEU WHH*, Shieh SM, Fuh MMT, Shen DC, Jeng CY, Chen YDI, Reaven GM. Insulin resistance, glucose intolerance and hyperinsulinemia: hypertriglyceridemia versus hypercholesterole-mia. Arteriosclerosis and Thrombosis 13:367-370, 1993.
19. Jeng CY, SHEU WHH, Jaspan JB, Polonsky KS, Chen YDI, Reaven GM: Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 77:6-10, 1993.
20. Wang DJ, Shen DC, SHEU WHH, Chu NF, Fuh MMT, Chen L-M: Effect of nicardipine treatment on carbohydrate and lipoprotein metabolism in patients with hypertension. Clin and Exper Hypertension 15:557-574, 1993.
21. Young MH, Jeng CY, SHEU WHH, Shieh SM, Fuh MMT, Chen YDI, Reaven GM. Insulin resistance, glucose intolerance, hyperinsulinemia and dyslipidemia in patients with angiographically demonstrated coronary artery diease. Am J Cardiol 72:458-460, 1993.
22. Fuh MMT, Jeng CY, Young MS, SHEU WHH, Chen YDI, Reaven GM. Insulin resistance, glucose intolerance and hyperinsulinemia in patients with microvascular angina. Metabolism 42:1090-1092, 1993.
23. SHEU WHH*, Kung IL, Hsieh SY, Tang FC, Fuh MMT. Resting metabolic rate and proportions of fuels oxidation in young Chinese males. J Med Sci 14:103-110, 1993.
24. SHEU WHH*, Shieh SM, Shen DDC, Fuh MMT, Jeng CY, Chen YDI, Reaven GM. Effect of pravastatin treatment on glucose, insulin, and lipoprotein metabolism in patients with hypercholesterolemia. Am Heart J 127:331-336, 1994.
25. SHEU WHH*, Hsu CH, Chen YS, Jeng CY, Fuh MMT. Prospective evaluation of insulin resistance and lipid metabolism in women receiving oral contraceptives. Clin Endocrinol 40:249-255, 1994.
26. Jeng CY, Fuh MMT, SHEU WHH, Chen YDI, Reaven GM. Hormone and substrate modulation of plasma triglyceride concentration in primary hypertriglyceridemia. Endocrinology and Metabolism 1:15-21, 1994.
27. Lu KC, Shieh SD, Lin S, Chyr SH, Lin YF, Diang LK, Li BL, SHEU WHH, Ding YA. Hyperparathyroidism, glucose tolerance and platelet intracellular free calcium in chronic renal failure. Quartery J Med 87:359-365, 1994.
28. SHEU WHH*, Jeng CY, Shieh SM, Fuh MMT. Hepatic insulin extraction and insulin clearance in patients with hypertension. Clin and Exper Hypertension 16:691-707, 1994.
29. Jeng CJ, SHEU WHH, Fuh MMT, Chen YDI, Reaven GM. Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM. Diabetes 43:1440-1444, 1994.
30. Maheux P, Jeppesen J, SHEU WHH, Hollenbeck CB, Clinkingbeard C, Greenfiled MS, Chen YDI, Reaven GM. Additive effects of obesity, hypertension, and type 2 diabetes on insulin resistance. Hypertension 24:695-668, 1994.
31. Tang FC, Kung IL, Hsieh SY, SHEU WHH, Chang JB. Effects of a very-low-calorie diet and aerobic exercise on the metabolism of skeletal muscle. J Chin Nutri Soci 20:239-248, 1995.
32. Fuh MMT, Yin CS, Pei D, SHEU WHH, Jeng CY, Chen YDI, Reaven GM. Resistance to insulin-mediated glucose uptake and hyperinsulinemia in women who had preeclampsia during pregnancy. Am J Hypertens 8:768-771, 1995.
33. Su HY, SHEU WHH, Chin HML, Jeng CY, Chen YDI, Reaven GM. Effect of weight loss on blood pressure and insulin resistance in normotensive and hypertensive obese individuals. Am J Hypertens 8:1067-1071, 1995.
34. SHEU WHH*, Jeng CY, Shieh SM, Fuh MMT. Suppression of non-esterified fatty acid concentrations in patients with hypertension. Chin Med J (Taipei) 56:367-372, 1995.
35. SHEU WHH*, Wei J, Jeng CY, Fuh MMT, Chen YDI. Metabolic abnormalities following heart transplantation in patients with idiopathic cardiomyopathy. Horm Metab Res 27:469-472, 1995.
36. SHEU WHH*, Jeng CY, Fuh MMT, Chen YDI, Reaven GM. Effect of glipizide treatment on response to an infused glucose load in patients with NIDDM. Diabetes Care 18:1582-1587, 1995.
37. SHEU WHH*, Jeng CY, Fuh MMT, Chen YDI, Reaven GM. Resistance to insulin-mediated glucose disposal in patients with noninsulin-dependent diabetes mellitus in the absence of obesity or microalbuminuria - a clinical research center study. J Clin Endocrinol Metab 81:1156-1159, 1996.
38. Jeng JR, SHEU WHH, Huang SH , Shieh SM. Impaired fibrinolysis and insulin resistance in patients with hypertension. Am J Hypertens 9:484-490, 1996.
39. Jeng JR, SHEU WHH, Jeng CY, Huang SH , Shieh SM. Effect of doxazosin on fibrinolysis in hypertensive patients with and without insulin resistance. Am Heart J 132:783-789, 1996.
40. Wu DA, Bu XD, Warden CH, Shen DDC, Jeng CY, SHEU WHH, Fuh MMT, Katsuya T, Dzau VJ, Reaven GM, Lusis AJ, Rotter JI, Chen YDI. Quantitative trait locus mapping of human blood pressure to the lipoprotein lipase gene locus on chromosome 8p22. J Clin Invest 97:2111-2118, 1996.
41. Jeng CY, SHEU WHH, Fuh MMT, Shieh SM, Chen YDI, Reaven GM. Gemfibrozil treatment of endogenous hypertriglyceridemia: effect on insulin-mediated glucose disposal and plasma insulin concentrations. J Clin Endocrinol & Metab 81:2550-2553, 1996.
42. Bau CT, SHEU WHH*, Song YM, Tseng LN, Wang CC. Acanthosis nigricans and diabetic ketoacidosis. Diabetes Care 20:1202, 1997.
43. Jeng JR, Shieh SM, Harn HJ, Lee MMS, SHEU WHH, Jeng CY. Angiotensin I converting enzyme gene polymorphism and insulin resistance in patients with hypertension. J Hypertens 15:963-968, 1997.
44. Jeng JR, Jeng CY, SHEU WHH, Lee, MMS, Huang SH , Shieh SM. Gemfibrozil treatment of hypertriglyceridemia: improvement on fibrinolysis without change of insulin resistance. Am Heart J 134:565-571, 1997.
45. Ding YA, SHEU WHH, Hu CA, Pei D. Effect of fluvastatin on non-insulin-dependent diabetes mellitus with hypercholesterolemia. Acta Sinica Cardiologica 13:138-144, 1997.
46. Chen MD, Lin PY, SHEU WHH. Zinc status in plasma of obese individuals during glucose administration. Biol Trace Element Res 60:123-129, 1997.
47. SHEU WHH*, Lee, W-J. Abnormal gonadotropin release and carbohydrate metabolism in morbid obese women. Chinese J Physiology 40:207-212, 1997.
48. SHEU WHH*, Lee WJ, Jeng CY, Young MS, Ding YA, Chen YT. Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease. Am Heart J 136:125-131, 1998.
49. SHEU WHH*, Chin HML, Su HY, Jeng CY. Effect of weight loss on resting energy expenditure in hypertensive and normotensive obese women. Clin Exper Hypertens 20:403-416, 1998.
50. Wu CJ, SHEU WHH. Type 2 diabetes mellitus in adult patient with pseudopseudohypoparathyroidism. A case report. Diabetes Care 21:1575-1576, 1998.
51. Pei D, SHEU WHH, Jeng CY, Liao WK, Fuh MMT . Insulin resistance in patients with Klinefelter’s syndrome and idiopathic gonadotropin deficiency. J Formos Med Assoc 97:534-540, 1998.
52. Tseng NL, SHEU WHH, Cheung BMH, Song YM. Blood lipid distribution in patients with newly diagnosed non-insulin-dependent diabetes mellitus. Acta Cardiologica Sinica 14:58-63, 1998.
53. Lee WJ, SHEU WHH, Shu SG, Yao YE. Genetic analysis of the insulin receptor gene in Chinese patients with extreme insulin resistance. Chin Med J (Taipei) 61:636-642, 1998.
54. Wu CJ, Chen HL, Song YM, SHEU WHH, Chen SH. Mixed medullary-follicular carcinoma and palpillary carcinoma of the same thyroid. Intern Med 37:955-957, 1998.
55. SHEU WHH*, Lee WJ, Yao YE, Jeng CY, Young MMS, Chen YT. Lack of association between genetic variation in the 3 adrenergic receptor gene and insulin resistance in patients with coronary heart disease. Metabolism 48:651-654, 1999.
56. SHEU WHH*, Song YM, Lee WJ, Yao YE, Bau CT, Bai CL. Family aggregation and maternal inheritance of Chinese NIDDM in Taiwan. Chin Med J (Taipei) 62:146-151, 1999.
57. SHEU WHH*, Lee WJ, Chen YT. Sex difference of leptin concentrations and insulin sensitivity in nondiabetic Chinese subjects. Int J Obes 23:754-759, 1999.
58. SHEU WHH*, Lee WJ, Chen YT. Higher plasma leptin concentration in hypertensive men but not in hypertensive women. J Hypertens 17:1289-1295, 1999.
59. SHEU WHH*, Chung BL , Chen YT, Lin CJ, Lee WJ. Endothelial dysfunction is not reversed by simvastatin treatment in type 2 diabetes mellitus patients wit hypercholesterolemia. Diabetes Care 22:1224-1225, 1999.
60. Song YM, SHEU WHH, Lee WJ, Wu CJ, Kao CH. Plasma leptin concentrations are related to body fat mass and gender but not to thyroid dysfunction. Kaohsiung J Med Sci 15:119-126, 1999.
61. Wu CJ, Song YM, SHEU WHH. Short stature in a 46, XX male adolescent. Southern Med J 92:921-923, 1999.
62. Lin SY, SHEU WHH*, Lee WJ, Song YM, Chen YT. The Trp64Arg polymorphism of 3-adrenergic receptor gene is associated with increased plasma leptin level in obese Chinese women. Chin Med J (Taipei) 62:569-576, 1999.
63. Hsu CW, Ho CL, SHEU WHH, Harn HJ, Chao TY. Adrenal insufficiency caused by primary aggressive non-Hodgkin’s lymphoma of bilateral adrenal glands: report of a case and literature review. Ann Hematol 78:151-154, 1999.
64. Chen MD, Lin PY, Sheu WHH. Zinc coadministration attenuates melatonin’s effect on nitric oxide production in mice. Biological Trace Element Research 69:261-268, 1999.
65. Chin H-ML, SHEU WHH, Su HY. Effect of weight reduction on serum uric acid, urinary excretion of uric acid and insulin resistance in obese individuals. Nutrition Sciences Journal 24:167-177, 1999.
66. Yan SH, SHEU WHH*, Song Y-M, Tseng L-N. The occurrence of diabetic ketoacidosis in adults. Intern Med 39:10-14, 2000.
67. SHEU WHH*, Lee WJ, Chen YT. Plasma homocysteine concentrations and insulin sensitivity in hypertensive subjects. Am J Hypertens 13:14-20, 2000.
68. SHEU WHH*, Lee WJ, Jeng CY, Young MS, Chen YT. Coronary artery risk factor predicted by insulin resistance, plasma lipids and hypertension in nondiabetic individuals. Am J Med Sci 319:84-88, 2000.
69. Lee WJ, SHEU WHH, Jeng CJ, Young MS, Chen YT. Associations between lipoprotein lipase gene polymorphisms and insulin resistance in coronary heart disease. Chin Med J (Taipei) 63:563-572, 2000.
70. SHEU WHH*, Lee WJ, Chang RL, Chen YT. Plasma tumor necrosis factor levels and insulin sensitivity in hypertensive subjects. Clin Exper Hypertens 22:595-606, 2000.
71. Song YM, Lee WJ, Chen MD, Kao CH, SHEU WHH. Methylprednisolone increases plasma leptin levels in Graves’hyperthyroidism patients with active Graves’ ophthalmopathy. Horm Metab Res 32:251-300, 2000.
72. Tai TS, SHEU WHH*, Lee WJ, Yao HT, Chiang MT. Effect of chitosan on plasma lipoprotein concentrations in type 2 diabetic subjects with hypercholesterolemia. Diabetes Care 23:1703-1704, 2000.
73. Song YM, SHEU WHH. Pituitary tumor cosecreting thyrotropin and prolactin causing hyperthyroidism--a case report.      Kaohsiung J Med Sci 16:203-9, 2000.
74. Song YM, Chen MD, SHEU WHH. Effect of acarbose administration on plasma concentrations of zinc and copper in patients with NIDDM.     Kaohsiung J Med Sci 16:187-191, 2000.
75. Chen MD, Song YM, Tsou CT, Lin WH, SHEU WHH. Plasma concentrations of leptin and selected minerals do not differ in type 2 diabetic patients with or without sulfonylurea inefficacy. Diabetes Nutr Metab 13:284-286, 2000.
76. Chen MD, Song YM, Tsou CT, Lin WH, SHEU WHH. Leptin concentration and the Zn/Cu ratio in plasma in women with thyroid disorder. Biol Trace Elem Res 75:99-105, 2000.
77. Wu CJ, Song YM, SHEU WHH. Tertiary hyperparathyroidism in X-linked hypophosphatemic rickets. Internal Medicine 39:468-471, 2000.
78. Chen MD, SHEU WHH. Plasma status of selected minerals in hypertensive men with and without insulin resistance. J Trace Elem Med Biol 14:228-231, 2001.
79. SHEU WHH*, Wu HS, Wang CW, Wan CJ, Lee WJ. Elevated plasma homocysteine concentrations occur six months after gastroplasty in morbidly obese subjects. Intern Med 40:584-588, 2001.
80. SHEU WHH*, Jeng CY, Lee WJ, Lin SY, Pei D, Chen YT. Simvastatin treatment on postprandial hypertriglyceridemia in type 2 diabetes mellitus patients with combined hyperlipidemia. Metabolism 50:355-359, 2001.
81. Yu HI, SHEU WHH*, Lai CJ, Lee WJ, Chen YT. Endothelial dysfunction in type 2 diabetes mellitus subjects with peripheral artery disease. Inter J Cardiol 78:19-26, 2001.
82. Song YM, SHEU WHH, Lee WJ. Acute biochemical variations induced by calcium citrate and calcium carbonate in type 2 diabetic patients: impaired calcium absorption in type 2 diabetic patients with prolonged gastric emptying time. J Diabetes and its Complications 15:97-102, 2001.
83. SHEU WHH*, Chen YT, Lee WJ. Improvement in endothelial dysfunction with low density lipoprotein cholesterol level below 80 mg/dl in type 2 diabetes mellitus Patients. Diabetes Care 24:1499-1501, 2001.
84. SHEU WHH*, Lee WJ, Lin LY, Chang RL, Chen YT. Tumor necrosis factor -238 and -308 polymorphisms do not associate with insulin resistance in hypertensive subjects. Metabolism 50:1447-1451, 2001.
85. Chao CS, SHEU WHH*. Free fatty acids and hyperglycemia on vascular wall: What do we learn. Chin Med J (Taipei) 64:433-434, 2001.
86. Chung LM, Hsiung CA, Chen YDI, Ho LT, SHEU WHH, Pei D, Nakatsuka CH, Cox D, Pratt RE, Lei HH, Tai TY. Sibling-based association study of the PPARr2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. J Mol Med 79:656-664, 2001.
87. Ranade K, SHEU WHH, Hung YJ, Hsuing CA, Chiang FT, Pesich R, Hebert J, Olivier M, Chen YD, Pratt R, Olshen R, Curb D, Botstein D, Risch N, Cox DR. The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin. Am J Hypertens. 14:1196-200, 2001.
88. Ranade K, Jorgenson E, SHEU WHH, Pei D, Hsuing CA, Chiang FT, Chen YI, Pratt R, Olshen R, Curb D, Cox DR, Botstein D and Risch N. A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. American J Human Genetics 70: 935-942, 2002.
89. Lee YT, Lin SY, SHEU WHH. Serial body composition by bioimpedance analysis in diabetic subjects with rapid insulin-induced weight gain- a case report. Kaohsiung J Med Sci 18:45-48, 2002.
90. Lin SY, SHEU WHH, Chang MC, Tang KT, Lee TI, Lin HD. Diagnosis of thyroid metastasis in cancer patients with thyroid mass by fine needle aspiration cytology and ultrasonography. Chin Med J (Taipei) 65:101-105, 2002.
91. Chao CS, Lin SY, SHEU WHH, Ho WL. Thyroglossal duct cyst with papillary carcinoma. Chin Med J (Taipei) 65:183-186, 2002.
92. Chao CS, Lin SY, SHEU WHH. Graves' disease presented as painful goiter. Horm Res 57:53-6, 2002.
93. Wu KD, Hsiao CF, Ho LT, SHEU WHH, Pei D, Chuang LM, Curb D, Chen YDI, Tsai HJ, Dzau VJ, Cox D, Tai TY. Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: a Stanford-Asian Pacific Program in Hypertension and Insulin Resistance Sibling Study. Hypertens Res 25:529-536, 2002.
94. Lee IT, SHEU WHH, Lin SY. Hypoglycemia probably due to accidental intake of repaglinide. Chang Gung Med J 25:783-786, 2002.
95. Liao LC, Chen NS, Shaw KY, Tasi YT, SHEU WHH. Evaluation of interns’ clinical training in a medical center. J Med Education 6:303-313, 2002.
96. Hsu HY, Chen YT, SHEU WHH, Sheng WY, Chao AC. Comparison of brachial artery flow-mediated vasodilatation in symptomatic and asymptomatic patients with carotid arterial stenosis. Am J Cardiol. 90:814-816, 2002.
97. Lee IT, SHEU WHH*, Lin SY, Lee WJ, Song YM, Liu HC. Simvastatin reduces plasma concentration of high-sensitivity C-reactive protein in type 2 diabetic patients with hyperlipidemia. J Diabetes Complications. 16:382-385, 2002.
98. Lin SY, Wang YY, SHEU WHH. Increased serum leptin concentrations correlate with soluble tumor necrosis factor receptor levels in patients with cirrhosis. Clin Endocrinol (Oxf). 57:805-811, 2002.
99. Chen JL, SHEU WHH, Tai TS, Liaw YP, Chen YC. Konjac supplement alleviated hypercholesterolemia and hyperglycemia in type 2 diabetic subjects-a randomized double-blind trial. J Am Coll Nutr. 22:36-42, 2003.
100. Lee IT, SHEU WHH, Lin SY. Familial form of thyroid dysgenesis: report of thyroid hemiagenesis with accompanying graves' disease in a woman whose daughter has thyroid agenesis. Horm Res. 59(1):47-49, 2003.
101. SHEU WHH*, Chen YT, Lee WJ, Wang CW, Lin SY. A relationship between serum ferritin and the insulin resistance syndrome is present in non-diabetic women but not in non-diabetic men. Clin Endocrinol 58:380-385,2003.
102. Chen NS, Chao KY, Tsai YT, SHEU WHH, Shaw KY. Evaluation on the Quality of a Dental Internship Training Program. Journal of Medical Education 7: 38-50, 2003.
103. Chen NS, Chao KY, Feng SC, SHEU WHH, Tsai YT, Shaw KY. Evaluation of an Ambulatory Care Teaching Program in a Medical Center. Journal of Medical Education 7: 59-69, 2003.
104. Lin SY, Wang YY, SHEU WHH. Preoperative plasma concentrations of vascular endothelial growth factor and matrix metalloproteinase 9 are associated with stage progression in papillary thyroid cancer. Clin Endocrinol (Oxf) 58:513-518, 2003.
105. Hwu CM, Hsiao CF, SHEU WHH, Pei D, Tai TY, Quertermous T, Rodriguez B, Pratt R, Chen YD, Ho LT. Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings. J Hum Hypertens 17:193-198, 2003.
106. Lee IT, SHEU WHH*, Liau YJ, Lin SY, Lee WJ, Lin CC. Relationship of stressful life events, anxiety and depression to hyperthyroidism in an asian population. Horm Res 60: 247-251, 2003.
107. Tai TS, Lin SY, SHEU WHH. Metabolic effects of growth hormone therapy in an Alstrom syndrome patient. Horm Res 60: 297-301, 2003.
108. Lee IT, Lin SY, SHEU WHH. Mood disorder and secondary adrenal insufficiency after pituitary tumor operation and radiotherapy. J Chin Med Assoc 66: 375-378, 2003.
109. Chao KY, Feng SC, Chen NS, SHEU WHH, Shaw K-Y. A preliminary study on patients’ perception of a teaching clinic in a medical center. Journal of Medical Education 7: 247-257, 2003.
110. Wan CJ, SHEU WHH*, Hsu SL, Chiu YT. Curriculum evaluation on a life science medical camp for senior high students. Journal of Medical Education 7: 234-246, 2003.
111. Yu HI, SHEU WHH, Song YM, Liu HC, Lee WJ, Chen YT.C-reactive protein and risk factors for peripheral vascular disease in subjects with Type 2 diabetes mellitus. Diabet Med 21:336-341, 2004.
112. Lin SD, Tu ST, Sai HK, Hsu SR, Lin KC, SHEU WHH. Clinical application of hsCRP for cardiovascular disease detection and prevention. J Intern Med Taiwan 15: 43-48, 2004.
113. Lin RT, Lee WJ, Jeng CY, SHEU WHH, Chen YT. Metabolic syndrome and its contribution to coronary artery disease in non-diabetic subjects. J Formos Med Assoc 103:317-320, 2004.
114. Lu TM, Ding YA, Leu HB, Yin WH, SHEU WHH, Chu KM. Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia. Am J Cardiol. 94:157-161, 2004.
115. Lin SY, Wang YY, SHEU WHH. Increased serum soluble tumor necrosis factor receptor levels are associated with insulin resistance in liver cirrhosis. Metabolism 53:922-926, 2004.
116. Lee WL, SHEU WHH, Liu TJ, Lee WJ, Tsao CR, Ju YH, Liao MF, Chen YT, Ting CT. The short-/intermediate-term changes in novel vascular inflammatory markers after angioplasty plus stenting in patients with symptomatic advanced systemic arterial diseases. Atherosclerosis 176:125-132, 2004.
117. SHEU WHH*, Lee WJ, Chen YT. Combined use of fasting glucose and hemoglobin a levels in screening for new type 2 diabetes mellitus in elderly men: TCVGHAGE. J Am Geriatr Soc 52:1777-1778, 2004.
118. Chuang LM, Chiu YF, SHEU WHH, Hung YJ, Ho LT, Grove J, Rodriguez B, Quertermous T, Chen YD, Hsiung CA, Tai TY. Biethnic comparisons of autosomal genomic scan for loci linked to plasma adiponectin in populations of chinese and Japanese origin. J Clin Endocrinol Metab 89:5772-5778, 2004.
119. SHEU WHH*. The metabolic syndrome: What have we learned. J Chin Med Assoc 67:597-599, 2004.
120. Hung YJ, Hsieh CH, Pei D, Kuo SW, Lee JT, Wu LY, He CT, Lee CH, Fan SC, SHEU WHH. Rosiglitazone improves insulin sensitivity and glucose tolerance in subjects with impaired glucose tolerance. Clin Endocrinol 62:85-91, 2005.
121. Lin SY, Chen WY, Lee FY, Huang CJ, SHEU WHH*. Activation of Ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: Potential role of tumor necrosis factor-{alpha}. Am J Physiol Endocrinol Metab 288(3):E493-501, 2005.
122. SHEU WHH*, Lee WJ, Chin HML, Wan CJ, Su HY, Lang HF. Prospective evaluation of folic acid supplementation on plasma homocysteine concentrations during weight reduction: A randomized, double-blinded, placebo-controlled study in obese women. Life Sciences 76:2137-2145, 2005.
123. Lin SY, Chen WY, Chiu YT, Lee WJ, Wu HS, SHEU WHH*. Different Tumor Necrosis Factor-a-Associated Leptin Expression in Rats with Dimethylnitrosamine and Bile Duct Ligation-Induced Liver Cirrhosis. Metabolism. 54:445-452, 2005.
124. Lin SY, SHEU WHH, Chen WY, Lee FY, Huang CJ. Stimulated Resistin Expression in White Adipose of Rats with Bile Duct Ligation-Induced Liver Cirrhosis: Relationship to Cirrhotic Hyperinsulinemia and Increased Tumor Necrosis Factor-alpha. Mol Cell Endocrinol 232:1-8, 2005.
125. Hsu HY, Wang PY, Chen YT, SHEU WHH, Hu HH, Sheng WY. Changes in flow-mediated dilatation, cytokines and carotid arterial stenosis during aggressive atorvastatin treatment in normocholesterolemic patients. J Chin Med Assoc. 68:53-58, 2005.
126. Tseng ST, SHEU WHH, Lee WJ, Ting CT, Chen YT, Jeng CY. Relationship between several surrogate estimates of insulin sensitivity in non-diabetic patients with coronary artery disease. J Formos Med Assoc. 104:94-100, 2005.
127. Hung YJ, Chen YC, Pei D, Kuo SW, Hsieh CH, Wu LY, He CT, Lee CH, Fan SC, SHEU WHH. Sibutramine improves insulin sensitivity without alteration of serum adiponectin in obese subjects with Type 2 diabetes. Diabet Med 22:1024-1030, 2005.
128. Wang YY, Lin SY, Lai WA, Liu PH, SHEU WHH. Association between adenomas of rectosigmoid colon and metabolic syndrome features in a Chinese population. J Gastroenterol Hepatol 20:1410-1415, 2005.
129. Lee IT, Lin TM, Lee WJ, Ou HC, Chien YH, Yang CH, Lee WL, SHEU WHH*. Hypercholesterolemia, not metabolic syndrome, related to adhesion of monocytes to cultured endothelium in nondiabetic subjects. Metabolism 54:1467-1471, 2005.
130. Lin SY, Wang YY, Liu PH, Lai WA, SHEU WHH. Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population. Metabolism 54:1524-1528, 2005.
131. Wang JS, Chen YW, Ou HC, SHEU WHH. Exercise paradoxically modulates oxidized low density lipoprotein-induced adhesion molecules expression and trans-endothelial migration of monocyte in men. Thromb Haemost 94:846-852, 2005.
132. Chiou JB, Lin SY, Yen CH, SHEU WHH, Jeng CY. Efficacy and safety of a mixture of two different brands of insulin products in patients with type 1 diabetes mellitus. J Chin Med Assoc 68:517-521, 2005.
133. Chen Y-H, Hsieh T-Y, Chang M-F, Lan J-L, SHEU WHH*. Evaluation of airway management training rrogram in a medical center. J Med Education 9:308-319, 2005.
134. Pei D, Kuo SW, Wu DA, Lin TY, Hsieh MC, Lee CH, Hsu WL, Chen SP, SHEU WHH, Li JC. The relationships between insulin resistance and components of metabolic syndrome in Taiwanese Asians. Int J Clin Pract 59:1408-16, 2005.
135. Lee WJ, SHEU WHH, Chen YT, Ting CT, Lee WL. Circulating CD40 ligand is elevated only in patients with more advanced symptomatic peripheral arterial diseases. Thrombosis Research 118:619-626, 2006.
136. Ou HC, Chou FP, Sheen HM, Lin TM, Yang CH, SHEU WHH*. Resveratrol protect oxidized LDL-induced cytotoxicity and adhesion molecules expressions in endothelial cells. Clinica Chimica Acta 364:196-204, 2006.
137. SHEU WHH*, Ou HC, Chou FP, Lin TM, Yang CH. Rosiglitazone inhibit endothelial proliferation and angiogenesis. Life Science 78:1520-1528, 2006.
138. SHEU WHH*, Tseng YH. Uric acid: An additional component of metabolic syndrome ? J Chin Med Assoc 69:99-100, 2006.
139. Hung YJ, Lin SH, Pei D, Kuo SW, Hsieh CH, He CT, Hsing LC, Fan SC, SHEU WHH. Rosiglitazone improves insulin sensitivity in nonobese subjects with impaired glucose tolerance: the role of adiponectin and C-reactive protein. Metabolism 55:439-444, 2006.
140. Lee IT, SHEU WHH*, Tu ST, Kuo SW, Pei D. Bisphosphonates pretreatment ameliorates hungry bone syndrome postoperatively in subjects with primary hyperparathyroidism. J of Bone and Mineral Metabolism ;24:255-258, 2006.
14. Tseng LN, SHEU WHH*, Ho E, Hu CJ. Bisphosphate treatment for oteoprosis postmenopausal women: A 3-year prospective study. Metabolism 55:741-747, 2006.
142. Ou HC, Chou FP, Lin TM, Yang CH, SHEU WHH*. Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells. Food and Chemical Toxicology 44:1485-1495, 2006.
143. Ou HC, Chou FP, Lin TM, Yang CH, SHEU WHH*. Protective effects of honokiol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells. Biol-Chemi Interaction 161:1-13, 2006.
144. SHEU WHH, Chuang SY, Lee WJ, Tsai ST, Chou P, Chen CH. Predictors of incident diabetes, metabolic syndrome in middle-aged adults: A 10-year follow-up study from Kinmen, Taiwan. Diabetes Research and Clinical Practice 74:162-168, 2006.
145. Ho J Y-P, Chen MJ, SHEU WHH, Yi YC, Tsai ACW, Guu HF, Ho ESC. Differential effects of oral conjugated equine estrogen and transdermal estrogen on atherosclerotic vascular disease risk markers and endothelial function in healthy postmenopausal women. Human Reprod 21:2715-2720, 2006.
146. Liang K, SHEU WHH, Lee WL, Liu TJ, Ting CT, Chen YT, Lee WJ. Coronary artery disease progression is associated with C-reactive protein and conventional risk factors but not soluble CD40 ligand. Can J Cardiol. 22:691-696, 2006.
147. Tseng LN, Sheu WHH*, Ho ES, Lan HH, Hu CC, Kao CH. Effects of alendronate combined with hormone replacement therapy on osteoporotic postmenopausal Chinese women. Metabolism. 55:741-747, 2006.
148. Lee WL, Lee WJ, Chen YT, Liu TJ, Liang KW, Ting CT, SHEU WHH*. The presence of metabolic syndrome is independently associated with elevated serum CD40 ligand and disease severity in patients with symptomatic coronary artery disease. Metabolism 55:1029-1034, 2006.
149 Lin SY, Sheu WHH*. An emerging link between insulin resistance and inflammation. J Chin Med Assoc. 69:245-247, 2006.
150. Lin MW, Hwu CM, Huang YH, SHEU WHH, Shih KC, Chiang FT, Olshen R, Chen YD, Curb JD, Rodriguez B, Ho LT; SAPPHIRe Study Group. Directly measured insulin resistance and the assessment of clustered cardiovascular risks in hypertension. Am J Hypertens 19:1118-1124, 2006.
151. Lin SD, Tu ST, Hsu SR, Lin KC, SHEU WHH. Characteristics predicting dyslipidemia in drug-naive type 2 diabetes patients. J Chin Med Assoc. 69:404-408, 2006.
152. Chen PL, Wang PY, SHEU WHH, Chen YT, Ho YP, Hu HH, Hsu HY. Changes of brachial flow-mediated vasodilation in different ischemic stroke subtypes. Neurology. 67:1056-1058, 2006.
153. Chuo LJ, SHEU WHH, Pai MC, Kuo YM. Genotype and plasma concentration of cystatin C in patients with late-onset Alzheimer disease. Dement Geriatr Cogn Disord. 23:251-257, 2007.
154. Hsieh CH, Hung YJ, Wu DA, Kuo SW, Lee CH, SHEU WHH, Li JC, Yeh KH, Chen CY, Pei D. Impact of clinical characteristics of individual metabolic syndrome on the severity of insulin resistance in chinese adults. J Korean Med Sci. 22:74-80, 2007.
155. Ou HC, Chou FP, SHEU WHH, Hsu SL, Lee WJ. Protective effects of magnolol against oxidized LDL-induced apoptosis in endothelial cells. Arch Toxicol. 81(6):421-32, 2007.
156. Tang YJ, SHEU WHH, Liu PH, Lee WJ, Chen YT. Positive associations of bone mineral density with body mass index, physical activity, and blood triglyceride level in men over 70 years old: a TCVGHAGE study. J Bone Miner Metab. 25:54-59, 2007.
157. Hsu CW, Chen HH, SHEU WHH, Chu SJ, Shen YS, Wu CP, Chien KL. Initial Serum Glucose Level as a Prognostic Factor in the First Acute Myocardial Infarction. Ann Emerg Med. 49(5):618-26, 2007
158. Chang MF, Li GL, Chen NS, SHEU WHH*. Evaluation of instructors learning course at one medical center. Hospital 40:53-62, 2007.
159. Lin CS, SHEU WHH, Chern CM, Wu CC, Ho LT, Hsu CY, Hsu TL, Lo YK, Chen MF. The best usage of aspirin in primary prevention-Indication, dosage and ethnic issues. J Intern Med Taiwan 18:1-10, 2007.
160. Hung YJ, Hsieh CH, Chen YJ, Pei D, Kuo SW, Shen DC, SHEU WHH, Chen YC. Insulin sensitivity, proinflammatory markers and adiponectin in young males with different subtypes of depressive disorder. Clin Endocrinol (Oxf). 67(50):784-9, 2007.
161. Liang KW, SHEU WHH, Lee WL, Liu TJ, Ting CT, Hsieh YC, Wang KY, Chen YT, Lee WJ. Decreased circulating protective adiponectin level is associated with angiographic coronary disease progression in patients with angina pectoris. Int J Cardiol. 2007.
162. Tang YJ, Lee WJ, Chen YT, Liu PH, Lee MC, SHEU WHH*. Serum testosterone level and related metabolic factors in men over 70 years old. J Endocrinol Invest: 30(6):451-8, 2007.
163. SHEU WHH*, Chen YD, Yu CY, Guo X, Lee TC, Lee WJ, Chen YT, Rotter JI. C-reactive protein gene polymorphism 1009A>G is associated with serum CRP levels in Chinese men: a TCVGHAGE study. Clin Chim Acta. 382(1-2):117-23, 2007.
164. Huang SC, Wu VC, Chou G, Huang TY, Lin SY, SHEU WHH. Benign parathyroid adenoma presenting with unusual parathyroid crisis, anemia and myelofibrosis. J Formos Med Assoc: 106 (2 Suppl):S13-6, 2007.
165. Nestel P, Lyu R, Low LP, SHEU WHH, Nitiyanant W, Saito I, Tan CE. Metabolic syndrome: recent prevalence in East and Southeast Asian populations. Asia Pac J Clin Nut: 16:362-7, 2007.
166. Lin JW, SHEU WHH, Lee WJ, Chen YT, Liu TJ, Ting CT, Lee WL. Circulating hepatocyte growth factor level but not basic fibroblast growth factor level is elevated in angiography-proven symptomatic peripheral artery disease. Angiology: 58:420-8, 2007.
167. SHEU WHH*. Meatabolic syndrome in uremic subjects: another facet is emerging. Acta Nephrologica: 21: 193-194, 2007.
168. Chien HH, Chang CT, Chu NF, Hsieh SH, Huang YY, Lee IT, Lee WJ, Tang YJ, SHEU WHH*. Effect of glyburide-metformin combination tablet in patients with type 2 diabetes. J Chin Med Assoc 70: 473-480, 2007.
169. Wang JS, SHEU WHH*, Dysglycemia and Cardiovascular disease. The Endo Soc. & The Diabetes Assoc of the ROC: 20(4): 1-10, 2007.
170. Chang YC, Lin SY, SHEU WHH*, Yang CS, Wang J. Silent Somatotrophinoma: A case report. The Endo Soc. & The Diabetes Assoc of the ROC: 20: 46-51, 2007.
171. Chien HH, Chang CT, Chu NF, Hsieh SH, Huang YY, Lee IT, Lee WJ, Tang YJ, SHEU WHH*. Effect of glyburide-metformin combination tablet in patients with type 2 diabetes. J Chin Med Assoc. 70(11):473-80, 2007.
172. Lee IT, Lee WJ, Huang CN, SHEU WHH*. The association of low-grade inflammation, urinary albumin, and insulin resistance with metabolic syndrome in nondiabetic Taiwanese. Metabolism 56: 1708-13, 2007.
173. Wang CW, Tschen JSM, SHEU WHH*. Ganoderma lucidum on metabolic control in type 2 diabetes: A double blinded placebo control study. J Intern Med Taiwan 19:54-60, 2007.
174. Liang KW, Lee WJ, Lee WL, Chen YT, Ting CT, SHEU WHH*. Diabetes exacerbates angiographic coronary lesion progression in subjects with metabolic syndrome independent of CRP levels. Clin Chim Acta. 338:41-5, 2008.
175. Liang KW, SHEU WHH, Lee WL, Liu TJ, Ting CT, Hsieh YC, Wang KY, Chen YT, Lee WJ. Decreased circulating protective adiponectin level is associated with angiographic coronary disease progression in patients with angina pectoris. Int J Cardiol 129:76-80, 2008.
176. Lee WJ, Lee WL, Tang YJ, Liang KW, Chien YH, Tsou SS, SHEU WHH*. Early Improvements in insulin sensitivity and inflammatory markers are induced by pravastatin in nondiabetic subjects with hypercholesterolemia. Clin Chim Acta 390:49-55, 2008.
177. SHEU WHH*, Chang TM, LeeWJ, Ou HC, Wu CM, Tsent LN, Lang HF, Wu CS, Wan CJ, Lee IT. Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Obesity 16:1033-1038, 2008.
178. Wu MC, Lee WJ, TschenSM, Lin SY, Lee IT, Jeng CY, Tseng LN, Liu YM, Chen BY, SHEU WHH*. Predictors of mortality in hospitalized diabetic patient: A 7-year prospective study. Diabetes Res Clin Pract 80:449-454, 2008.
179. Lee IT, Huang CN, Lee WJ, Lee HS, SHEU WHH*. High total-to-HDL cholesterol ratio predicting deterioration of ankle brachial index in Asian type 2 diabetic subjects. Diabetes Res Clin Pract. 2008 Mar;79(3):419-26. Epub 2007 Nov 14.
180. Lee WJ, Lee WL, Tang YJ, Liang KW, Chien YH, Tsou SS, SHEU WHH*. Early Improvements in insulin sensitivity and inflammatory markers are induced by pravastatin in nondiabetic subjects with hypercholesterolemia. Clin Chim Acta 390:49-55. 2008.
181. Sung SH, Chuang SY, SHEU WHH, Lee WJ, Chou P, Chen CH. Adiponectin, but not leptin or high-sensitivity C-reactive protein, is associated with blood pressure independently of general and abdominal adiposity. Hypertens Res. 31:633-40. 2008.
182. Lee IT, Huang CN, Lee WJ, Lee HS, SHEU WHH*. Aggravation of albuminuria by metabolic syndrome in type 2 diabetic Asian subjects. Diabetes Res Clin Pract. 2008 Sep;81(3):345-50. Epub 2008 Jul 15.
183. SHEU WHH, Lee IT, Chen YA, Chang YC:Effects of xylooligosaccharides in type 2 diabetes mellitus. J Nutr Sci Vitaminol 54, 396-401, 2008.
184. Lee IT, Chan YC, Lin CW, Lee WJ, SHEU WHH*. Effect of cranberry extracts on lipid profiles in subjects with Type 2 diabetes. Diabet Med 25:1473-7, 2008.
185. Wang JS, Lin SY, Sheu WH, Lee IT, Tseng LN, Song YM. Effects of patient volume on quality of outpatient diabetes care. Diabetes Res Clin Pract. 2009 May;84(2):e27-9. Epub 2009 Mar 9.
186. Huang SC, Wu VC, Lin SY, SHEU WHH, Song YM, Lin YH, Wu CC, Chang WD. Factors related to clinical hypothyroid severity in thyroid cancer patients after thyroid hormone withdrawal. Thyroid 19:13-20, 2009.
187. Lee IT, Lee WJ, Ou HC, Huang CN, SHEUWHH*. Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia. Metabolism ;58:416-20, 2009.
188. Lee WJ, Lee WJ, Wu CS, Lin H, Lee IT, Wu CM, Tseng JJ, Chou MM, SHEU WHH*. Visfatin-induced expression of inflammatory mediators in human endothelial cells through the NF-kappaB pathway. Int J Obes (Lond). 2009 Feb 17.
189. Ou HC, Lee WJ, Lee IT, Chiu TH, Tsai KL, Lin CY, SHEU WHH*. Ginkgo biloba extract attenuates oxLDL-induced oxidative functional damages in endothelial cells. J Appl Physiol. 2009 Feb 19.
190. Lee IT, Liu HC, Liau YJ, Lee WJ, Huang CN, Sheu WH. Improvement in health-related quality of life, independent of fasting glucose concentration, via insulin pen device in diabetic patients. J Eval Clin Pract. 2009 Aug;15(4):699-703.
191. Chang CH, Chen YM, Chuang YW, Liao SC, Lin CS, Tang YJ, Sheu WH, Chen DY. Relationship between hyperuricemia (HUC) and metabolic syndrome (MS) in institutionalized elderly men. Arch Gerontol Geriatr. 2009 Dec;49 Suppl 2:S46-9.
192. Chou YY, Sheu WH, Tang YJ, Chen YM, Liao SC, Chuang YW, Lin CS, Chen DY. Plasminogen activator inhibitor type 1 (PAI-1) is a valuable biomarker for predicting the metabolic syndrome (MS) in institutionalized elderly residents in Taiwan. Arch Gerontol Geriatr. 2009 Dec;49 Suppl 2:S41-5.
193 Tseng YH, Huang KC, Liu ML, Shu WT, Sheu WH. Association between metabolic syndrome (MS) and bone mineral loss: a cross-sectional study in Puli Township in Taiwan. Arch Gerontol Geriatr. 2009 Dec;49 Suppl 2:S37-40.
194. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL, Lee SD, Sheu WH. Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. J Agric Food Chem. 2009 Dec 9;57(23):11406-17.
195. Chang YC, Chiu YF, Shih KC, Lin MW, Sheu WH, Donlon T, Curb JD, Jou YS, Chang TJ, Li HY, Chuang LM. Common PCSK1 haplotypes are associated with obesity in the Chinese population. Obesity (Silver Spring). 2010 Jul;18(7):1404-9. Epub 2009 Oct 29.
196. Wang YY, Lin SY, Sheu WH, Liu PH, Tung KC. Obesity and diabetic hyperglycemia were associated with serum alanine aminotransferase activity in patients with hepatitis B infection. Metabolism. 2010 Apr;59(4):486-91. Epub 2009 Oct 20.
197. Wang YY, Lin SY, Chuang YH, Mao CH, Tung KC, Sheu WH. Protein nitration is associated with increased proteolysis in skeletal muscle of bile duct ligation-induced cirrhotic rats. Metabolism. 2010 Apr;59(4):468-72. Epub 2009 Oct 20.
198. Lin SY, Huang SC, Sheu WH. Circulating adiponectin concentrations were related to free thyroxine levels in thyroid cancer patients after thyroid hormone withdrawal. Metabolism. 2010 Feb;59(2):195-9. Epub 2009 Sep 17.
199. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL, Lee SD, Sheu WH. Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. J Agric Food Chem. 2009 Dec 9;57(23):11406-17.
200. Tsai HJ, Hsiao CF, Ho LT, Chuang LM, He CT, Curb JD, Quertermos T, Hsiung CA, Sheu WH. Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population. Clin Chim Acta. 2010 Dec 14;411(23-24):2009-13. Epub 2010 Aug 23.
201. Lee IT, Liau YJ, Lee WJ, Huang CN, Sheu WH. Continuous subcutaneous insulin infusion providing better glycemic control and quality of life in Type 2 diabetic subjects hospitalized for marked hyperglycemia. J Eval Clin Pract. 2010 Feb;16(1):202-5. No abstract available. 
202. Lee IT, Lee WJ, Sheu WH. Metabolic syndrome exacerbating ankle-brachial index in asian type 2 diabetic patients. Angiology. 2010 Jul;61(5):482-6. Epub 2010 Apr 14.
203. Ou HC, Lee WJ, Lee SD, Huang CY, Chiu TH, Tsai KL, Hsu WC, Sheu WH. Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. Toxicol Appl Pharmacol. 2010 Oct 15;248(2):134-43. Epub 2010 Aug 4.
204. Lee WJ, Ou HC, Hsu WC, Chou MM, Tseng JJ, Hsu SL, Tsai KL, Sheu WH. Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells. J Vasc Surg. 2010 Nov;52(5):1290-300. Epub 2010 Aug 8.
205. Chen YM, Chen HH, Lan JL, Chen DY, Sheu WH. Nodular mucinosis in Graves disease mimicking gouty tophi. J Clin Rheumatol. 2010 Sep;16(6):287-9.
206. Wang JS, Tu ST, Lee IT, Lin SD, Lin SY, Su SL, Lee WJ, Sheu WH. Contribution of postprandial glucose to excess hyperglycaemia in Asian type 2 diabetic patients using continuous glucose monitoring. Diabetes Metab Res Rev. 2011 Jan;27(1):79-84. doi: 10.1002/dmrr.1149. Epub 2010 Nov 10.
207. Sheu WH, Chuang HC, Cheng SM, Lee MR, Chou CC, Cheng FC. Microdialysis combined blood sampling technique for the determination of rosiglitazone and glucose in brain and blood of gerbils subjected to cerebral ischemia. J Pharm Biomed Anal. 2011 Mar 25;54(4):759-64. Epub 2010 Oct 16.
208. Wang YY, Lin SY, Chuang YH, Chen CJ, Tung KC, Sheu WH. Adipose proinflammatory cytokine expression through sympathetic system is associated with hyperglycemia and insulin resistance in a rat ischemic stroke model. Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E155-63.
209.Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN. Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in TNF-α-treated human aortic endothelial cells. J Nutr Biochem. 2011 Feb;22(2):187-94.
210. Chiang SC, Lee JK, Chen CH, Chuang LM, Tsan KW, Sheu WH, Wu DA, Wu TJ, Lin KC, Juang JH, Wang CY, Ho LT. Justifying the high prevalence of microalbuminuria for type 2 diabetic patients in Taiwan with conditional probability approach- a DEMAND II study. J Chin Med Assoc. 2011 Jan;74(1):3-10.
211. Kuo MY, Ou HC, Lee WJ, Kuo WW, Hwang LL, Song TY, Huang CY, Chiu TH, Tsai KL, Tsai CS, Sheu WH. Ellagic acid inhibits oxidized low-density lipoprotein (OxLDL)-induced metalloproteinase (MMP) expression by modulating the protein kinase C-α/extracellular signal-regulated kinase/peroxisome proliferator-activated receptor γ/nuclear factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) signaling pathway in endothelial cells. J Agric Food Chem. 2011 May 11;59(9):5100-8.
212. Wang JS, Tu ST, Lee IT, Lin SD, Lin SY, Su SL, Lee WJ, Sheu WH. Contribution of postprandial glucose to excess hyperglycaemia in Asian type 2 diabetic patients using continuous glucose monitoring. Diabetes Metab Res Rev. 2011 Jan;27(1):79-84.
213. Sheu WH, Rosman A, Mithal A, Chung N, Lim YT, Deerochanawong C, Soewondo P, Lee MK, Yoon KH, Schnell O. Addressing the burden of type 2 diabetes and cardiovascular disease through the management of postprandial hyperglycaemia: An Asian-Pacific perspective and expert recommendations. Diabetes Res Clin Pract. 2011 Jun;92(3):312-21.
214. Sheu WH, Chuang HC, Cheng SM, Lee MR, Chou CC, Cheng FC. icrodialysis combined blood sampling technique for the determination of rosiglitazone and glucose in brain and blood of gerbils subjected to cerebral ischemia. J Pharm Biomed Anal. 2011 Mar 25;54(4):759-64.
215. Lang HF, Chou CY, Sheu WH, Lin JY. Weight loss increased serum adiponectin but decreased lipid levels in obese subjects whose body mass index was lower than 30 kg/m(2). Nutr Res. 2011 May;31(5):378-86.
216. Liang KW, Lee WJ, Lee IT, Lee WL, Lin SY, Hsu SL, Wan CJ, Yu CY, Tsai IC, Fu CP, Ting CT, Sheu WH. Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome. Clin Chim Acta. 2011 Sep 18;412(19-20):1835-41.
217. Lin SD, Wang JS, Hsu SR, Sheu WH, Tu ST, Lee IT, Su SL, Lin SY, Wang SY, Hsieh MC. The beneficial effect of α-glucosidase inhibitor on glucose variability compared with sulfonylurea in Taiwanese type 2 diabetic patients inadequately controlled with metformin: preliminary data. J Diabetes Complications. 2011 Sep-Oct;25(5):332-8.
218. Chan JC, Chan SP, Deerochanawong C, Go RT, Lee KO, Ma RC, Pan CY, Sheu WH, Barter P. Diabetic dyslipidaemia in Asian populations in the Western Pacific Region: What we know and don't know. Diabetes Res Clin Pract. 2011 Oct;94(1):1-13.
219. Wang JS, Lin SD, Lee WJ, Su SL, Lee IT, Tu ST, Tseng YH, Lin SY, Sheu WH. Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: a 24-week, andomized, open-label, parallel-group comparison. Clin Ther. 2011 Dec;33(12):1932-42.
220. Mu YM, Misra A, Adam JM, Chan SP, Chow FC, Cunanan EC, Deerochanawong C, Jang HC, Khue NT, Sheu WH, Tan KE. Managing diabetes in Asia: Overcoming obstacles and the role of DPP-IV inhibitors. Diabetes Res Clin Pract. 2012;95(2):179-88.
221.Sheen YJ, Lin JL, Lee IT, Hsu YN, Li TC, Sheu WH. Low estimated glomerular filtration rate is a major determinant of low ankle-brachial index and toe-brachial index in type 2 diabetes. Angiology. 2012 Jan;63(1):55-61.
222.Chang YC, Chiu YF, Liu PH, Shih KC, Lin MW, Sheu WH, Quertermous T, Curb JD, Hsiung CA, Lee WJ, Lee PC, Chen YT, Chuang LM. Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. Clin Endocrinol (Oxf). 2012 Mar;76(3):365-72.
223.Lee IT, Lee WJ, Tsai CM, Su IJ, Yen HT, Sheu WH. Combined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndrome. Nutr Res. 2012 Feb;32(2):85-92.
224.Lee IT, Lee WJ, Tsai IC, Liang KW, Lin SY, Wan CJ, Fu CP, Sheu WH. Brain-derived neurotrophic factor not associated with metabolic syndrome but inversely correlated with vascular cell adhesion molecule-1 in men without diabetes. Clin Chim Acta. 2012 May 18:413(9-10):944-8.
225.Mechanick JI, Marchetti AE, Apovian C, Benchimol AK, Bisschop PH, Bolio-Galvis A, Hegazi RA, Jenkins D, Mendoza E, Sanz ML, Sheu WH, Tatti P, Tsang MW, Hamdy O. Diabetes-specific nutrition algorithm: a transcultural program to optimize diabetes and prediabetes care. Curr Diab Rep. 2012 Apr;12(2):180-94.
226.Su HY, Tsang MW, Huang SY, Mechanick JI, Sheu WH, Marchetti A; Task Force for Development of Transcultural Algorithms in Nutrition and Diabetes. Transculturalization of a diabetes-specific nutrition algorithm: Asian application. Curr Diab Rep. 2012 Apr;12(2):213-9.
227.Liang KW, Tsai IC, Lee WJ, Lee IT, Lee WL, Lin SY, Wan CJ, Fu CP, Ting CT, Sheu WH. MRI measured epicardial adipose tissue thickness at the right AV groove differentiates inflammatory status in obese men with metabolic syndrome. Obesity (Silver Spring). 2012 Mar;20(3):525-32.
228.Ou HC, Lee WJ, Wu CM, Chen JF, Sheu WH. Aspirin prevents resistin-induced endothelial dysfunction by modulating AMPK, ROS, and Akt/eNOS signaling. J Vasc Surg. 2012 Apr;55(4):1104-15.
229.Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN. Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in TNF-α-treated human aortic endothelial cells. J Nutr Biochem. 2011 Feb;22(2):187-94.
230.Sheu WH, Ji LN, Nitiyanant W, Baik SH, Yin D, Mavros P, Chan SP. Hypoglycemia is associated with increased worry and lower quality of life among patients with type 2 diabetes treated with oral antihyperglycemic agents in the Asia-Pacific region. Diabetes Res Clin Pract. 2012 May;96(2):141-8.