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劉時安醫師

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最後更新時間:2018/9/12 10:34:39
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學歷

國立陽明大學醫學系醫學士      (1986.09 ~ 1993.05)

中國醫藥大學醫務管理學碩士  (2003.09 ~ 2005.05)

國立中興大學獸醫博士             (2005.09 ~ 2009.01)

 

經歷

竹東榮民醫院外科住院醫師               (1994.08 ~ 1996.08)

臺中榮民總醫院耳鼻喉科住院醫師  (1996.08 ~ 1999.07)

臺中榮民總醫院耳鼻喉科總醫師      (1999.08 ~ 2001.02)

臺中榮民總醫院耳鼻喉科主治醫師  (2001.03 ~ )

國立陽明大學部定助理教授            (2007.02 ~ 2013.01)

美國加大戴維斯分校醫學中心進修  (2007.07 ~ 2008.06)

美國史丹福大學醫學中心見習           (2007.11 ~ 2008.05)

美國ACRP認證臨床試驗主持人(CPI)(2009.10 ~ 2011.09)

台中榮民總醫院口腔咽喉科主任      (2010.01~  2013.10)

國立陽明大學部定副教授                 (2013.02~ 2018.01)

臺中榮民總醫院喉頭頸科主任          (2013.11~ 2017.12)

臺中榮民總醫院耳鼻喉頭頸部副主任   (2018.01~ )

教育部審定國立陽明大學專任教授      (2018.02~ )

 

門診時段:

每星期一, 三上午, 

睡眠 呼吸障礙手術特別門診 (約診, 無法自行預約), 每星期三下午

 

專長領域

口腔癌及其他頭頸部癌症之診斷與處理

甲狀腺腫瘤, 唾液腺腫瘤, 其他頭頸部腫瘤之診斷與處理

深頸部感染之診斷與處理

各類咽喉部炎症的診斷及治療

打鼾及睡眠呼吸中止症候群之診斷與處理

 

進行中計劃:

1. 頭頸部腫瘤患者之微衛星變異研究 (NSC 101-2314-B-075A-005-MY3)

2. 術中顏面神經監測對腮腺腫瘤切除患者生活品質之影響 (TCVGH-1067004C)

3. 以鄰位連接法找尋頭頸部腫瘤生物標記之研究 (MOST 104-2314-B-075A-010-MY3)

論文發表:(*通訊作者)

Liu SA*, Hsu CY, Jiang RS, Lin JC. Maxillary Swing Approach for Resection of Recurrent Nasopharyngeal Carcinoma –– Report of Three Cases. Journal of Taiwan Otolaryngology – Head and Neck Surgery 1999; 34:71-74.

Liu SA*, Hsu CY, Yu CY. Bedside Tracheostomy. Journal of Taiwan Otolaryngology – Head and Neck Surgery 2001; 36:225-229.

Liu SA*, Liu CY. Prevalence of snoring in Taichung area: An epidemiological study. J Chin Med Assoc 2004: 67: 32-36.

Li HY*, Wang PC, Hsu CY, Lee SW, Chen NH, Liu SA. Concomitant nasal and palatopharyngeal surgery for OSA: simultaneous or staged. Acta Oto-Laryngologica 2005; 125: 298-303 (SCI)

Liu SA*, Li HY, Tsai WC, Chang KM. Associated factors to predict outcomes of uvulopharyngopalatoplasty plus genioglossal advancement for obstructive sleep apnea. Laryngoscope 2005;115:2046-50 (SCI)

Liu SA*, Su MC, Jiang RS. Nasal patency measured by acoustic rhinometry in East Asian patients with sleep-disordered breathing. Am J Rhinol 2006;20:274-277 (SCI)

Wong YK, Tsai WC, Lin JC, Poon CK, Chao SY, Hsiao YL, Chan MY, Cheng CS, Wang CC, Wang CP, Liu SA*.  Socio-demographic factors in the prognosis of oral cancer patients. Oral Oncol 2006;42:893-906 (SCI)

Liu SA*, Tsai WC, Wong YK, Lin JC, Poon CK, Chao SY, Hsiao YL, Chan MY, Cheng CS, Wang CC, Wang CP. Nutritional factors and survival of oral cancer patients. Head Neck 2006;28:998-1007 (SCI)

Liu SA, Wong YK, Lin JC, Poon CK, Tung KC, Tsai WC*. Impact of recurrence interval on survival of oral cavity squamous cell carcinoma patients after local relapse. Otolaryngol Head Neck Surg 2007;136:112-118 (SCI)

Yang KY, Jiang RS, Shiao JY, Wang CC, Wang CP, Liang KL, Twu CW, Liu SA*. Visual Screening of oral cavity cancer -- The role of otolaryngologists. Laryngoscope 2007;117:92-95 (SCI)

Liu SA, Wong YK, Poon CK, Wang CC, Wang CP, Tung KC *. Risk factors for wound infection after surgery in primary oral cavity cancer patients. Laryngoscope 2007;117:166-171 (SCI)

Wang CC*, Lin CC, Wang CP, Liu SA, Jiang RS. Laryngeal tuberculosis: a review of 26 cases. Otolaryngol Head Neck Surg 2007;137:582-8 (SCI)

Lin CC, Wang CC*, Liu SA, Wang C-P, Chen W-H. Cervical sympathetic chain schwannoma. J Formos Med Assoc 2007;106:956-60 (SCI)

Jan JC, Wong YK, Poon CK, Wang CC, Wang CP, Liu SA *. Factors analysis of loco-regional recurrence in patients with oral cavity cancer. J Taiwan Otolaryngol Head Neck Surg 2007;42:115-127

Liu SA, Tung KC, Cheng CC, Chiu YT*. The impact of different closure materials on pharyngeal wound healing: an experimental animal study. Eur Arch Otorhinolaryngol 2008;265:227-31  (SCI)

Liu SA, Tung KC, Shiao JY, Chiu YT*. Preliminary report of associated factors in wound infection after major head and neck neoplasm operations. J Laryngol Otol 2008;122:403-8  (SCI)

Wang CC*, Chang MH, Wang CP, Liu SA. Prognostic indicators of unilateral vocal fold paralysis. Arch Otolaryngol Head Neck Surg 2008;134:380-388. (SCI)

Chen CC, Wang CC, Wang CP, Lin TH, Lin WD, Liu SA*. Prospective, randomized, controlled trial of tranexamic acid in patients undergoing head and neck procedures. Otolaryngol Head Neck Surg 2008;138:762-767. (SCI)

Liu SA, Chiu YT, Lin WD *, Chen SJ *. Using information technology to reduce the inappropriate use of surgical prophylactic antibiotic. Eur Arch Otorhinolaryngol  2008;265:1109-1112. (SCI)

Yen TT, Lin WD, Wang CP, Wang CC, Liu SA*. The association of smoking, alcoholic consumption, betel quid chewing and oral cavity cancer: A cohort study. Eur Arch Otorhinolaryngol 2008:265:1403-1407. (SCI)

Liang MT, Chen CCC, Wang CP, Wang CC, Lin WD, Liu SA*. The association of lymph node volume with cervical metastatic lesions in head and neck cancer patients. Eur Arch Otorhinolaryngol 2009;266:883-887. (SCI)

Liu SA, Liang MT, Wang CP, Wang CC, Lin WD, Ho HC, Chiu, YT *. Preoperative blood sugar and C-reactive protein associated with persistent discharge after incision and drainage for patients with deep neck abscesses. Clin Otolaryngol 2009;34:336-342 (SCI)

Lee YF, Cheng CC, Lin NN, Liu SA, Tung KC, Chiu YT *. Isolation of Trypanosoma (Megatrypanum) theileri from Dairy Cattle in Taiwan. J Vet Med Sci 2010;72:417-424 (SCI)

Hsieh YL, Jiang RS, Wang CP, Wang CC, Ho HC, Liu SA*. Risk factors of pneumothorax after totally implantable central venous access devices placement. J Taiwan Otolaryngol Head Neck Surg 2010;45(3): 69-75

Jan JC, Hsu WH, Liu SA, Wong YK, Poon CK, Jiang RS, Jan JS, Chen IF. Prognostic factors in patients with buccal squamous cell carcinoma: 10-year experience. J Oral MaxilloFac Surg 2011;69:396-404. (SCI)

Lin WJ, Jiang RS, Wu SH, Chen FJ, Liu SA*. Smoking, alcohol, betel quid and oral cancer - a prospective cohort study. Journal of Oncology vol 2011, Article ID 525976, 5 pages, 2011. doi:10.1155/2011/525976

Hsing CY, Wong YK, Wang CP, Wang CC, Jiang RS, Chen FJ, Liu SA*. Comparison between free flap and pectoralis major pedicled flap for reconstruction in oral cavity cancer patients – a quality of life analysis. Oral Oncol 2011;47:522-527 (SCI)

Liu SA, Wong YK, Wang CP, Wang CC, Jiang RS, Ho HC, Lin JC*. Surgical site infection after preoperative neoadjuvant chemotherapy in locally advanced oral squamous cell carcinoma patients. Head Neck 2011;33:954-8 (SCI)

Chang IH, Jiang RS, Wong YK, Wu SH, Chen FJ, Liu SA*. Visual screening of oral cavity cancer in male population -- Experience from a medical center. J Chin Med Assoc 2011;74:561-566 (SCI)

Lin WJ, Wang CP, Wang CC, Jiang RS, Wong YK, Chen FJ, Liu SA*. The association between surgical site infection and previous operation in oral cavity cancer patients. Eur Arch Otorhinolaryngol 2012;269:989-997 (SCI)

Chen CH, Hsu MY, Jiang RS, Wu SH, Chen FJ, Liu SA*. Shrinkage of head and neck cancer specimens after formalin fixation. J Chin Med Assoc 2012;75:109-113 (SCI)

Liu SA, Cheng CC, Chen JS, Hung YW, Chen FJ, Chiu YT*. Effect of oxidized regenerated cellulose on the healing of pharyngeal wound – an experimental animal study. J Chin Med Assoc 2012;75:176-182 (SCI)

Liu SA, Jiang RS, Chen FJ, Wang WY, Lin JC*. Somatic mutation in the D-loop of mitochondrial DNA in oral squamous cell carcinoma.  Eur Arch Otorhinolaryngol 2012;269:1665-1670 (SCI)

Wang YH, Kung PT, Tsai WC*, Tai CJ, Liu SA, Tsai MH. Effects of multidisciplinary care on the survival of patients with oral cavity cancer in Taiwan. Oral Oncol 2012;48:803-10 (SCI)

Lee YJ, Wang CC, Wang CP, Jiang RS, Liu SA*. Risk factors of surgical site infection after total laryngectomy. J Taiwan Otolaryngol Head Neck Surg 2013;48:45-54

Hsu SH, Wong YK, Wang CP, Wang CC, Jiang RS, Chen FJ, Liu SA*. Survival analysis of oral squamous cell carcinoma patients with simultaneous second primary tumors. Head Neck 2013;35:1801-1807 (SCI)

Wang JJ, Jiang RS, Huang YC, Liu SA*. Comparison between palatal implants and radiofrequency volume reduction in the management of snoring symptoms of patients with sleep-disordered breathing. J Taiwan Otolaryngol Head Neck Surg 2014;49:146-153.

Wang CC, Lien HC, Virgilio AD, Huang WC, Wu MF, Liu SA, Wang CP, Wu SH, Liang KL, Jiang RS. Airway pH monitoring in patients with suspected obstructive sleep apnea using the Dx-pH oropharyngeal probe: preliminary report of a prospective cohort study. Clin Otolaryngol2014;39:352-358. (SCI)

De Virgilio A, Chang MH, Jiang RS, Wang CP, Wu SH, Liu SA, Wang CC. Influence of Superior Laryngeal Nerve Injury on Glottal Configuration/Function of Thyroidectomy-Induced Unilateral Vocal Fold Paralysis. Otolaryngol Head Neck Surg 2014;151:996-1002.  (SCI)

Tsai WC, Kung PT, Wang ST, Hunag KW, Liu SA*. Beneficial impact of multidisciplinary team management on the survival in different stages of oral cavity cancer patients: results of a nationwide cohort study in Taiwan. Oral Oncol 2015;51:105-111 (SCI)

Chen YJ, Wang CP, Wang CC, Jiang RS, Lin JC, Liu SA*. Carotid blowout in head and neck cancer patients – associated factors and treatment outcomes. Head Neck 2015;37:265-272 (SCI)

Wang CC, Chang MH, Jiang RS, Lai HC, De Virgilio A, Wang CP, Wu SH, Liu SA, Liang KL. Laryngeal Electromyography-Guided Hyaluronic Acid Vocal Fold Injection for Unilateral Vocal Fold Paralysis: A Prospective Long-term Follow-up Outcome Report. JAMA Otolaryngol Head Neck Surg 2015 Mar;141(3):264-71. (SCI)

Lai CS, Chen IC, Liu SA, Lu CT, Yen JH, Song DY. Robot-assisted Free Flap Reconstruction of Oropharyngeal Cancer-A Preliminary Report. Ann Plast Surg. 2015;74 Suppl 2:S105-8.  (SCI)

Lin JC, Wang CC, Jiang RS, Wang WY, Liu SA*. Impact of Somatic Mutations in the D-loop of Mitochondrial DNA on the Survival of Oral Squamous Cell Carcinoma Patients. PLoS One 2015 Apr 23;10(4):e0124322.  (SCI)

Wang CC, Chang MH, De Virgilio A, Jiang RS, Lai HC, Wang CP, Wu SH, Liu SA. Laryngeal electromyography and prognosis of unilateral vocal fold paralysis-A long-term prospective study. Laryngoscope 2015 Apr;125(4):898-903. (SCI)

Liu SA, Jiang RS, Wang WY, Lin JC*. Somatic mutations in the D-loop of mitochondrial DNA in head and neck squamous cell carcinoma. Head Neck 2015 Jun;37(6):878-83 (SCI)

Lin YJ, Cheng FC, Chien LS, Lin JC, Jiang RS, Liu SA*. Expression of magnesium transporter genes in head and neck cancer patients underwent neoadjuvant cisplatin-based chemotherapy. Eur Arch Otorhinolaryngol 2015;272:3051–3057 (SCI)

Kuo TL, Jiang RS, Huang YC, Liu SA*. Preliminary report of a randomized controlled trial in postoperative pain between plasma knife-assisted versus traditional uvulopalatopharyngoplasty in sleep-disordered breathing patients. J Taiwan Otolaryngol Head Neck Surg 2015;50(2):82-89

Wang CH, Wong YK, Wang CP, Wang CC, Jiang RS, Lai CS, Liu SA*. Risk factors of recipient site infection in head and neck cancer patients undergoing pectoralis major myocutaneous flap reconstruction. Eur Arch Otorhinolaryngol 2015; 272(11):3475-3482 (SCI)

Huang CW, Wang CC, Jiang RS, Huang YC, Ho HC, Liu SA*. The impact of tissue glue in wound healing of head and neck patients undergoing neck dissection. Eur Arch Otorhinolaryngol 2016; 273(1):245-250. (SCI)

Lin JC, Wang CC, Jiang RS, Wang WY, Liu SA*. Microsatellite alteration in head and neck squamous cell carcinoma patients from a betel quid-prevalent region. Scientific Reports (UK) 2016; 6: 22614; doi:10.1038/srep22614 (SCI)

Chen JA, Wang CC, Wong YK, Wang CP, Jiang RS, Lin JC, Chen CC, Liu SA*. Osteoradionecrosis of mandible bone in oral cancer patients – associated factors and treatment outcomes. Head Neck 2016; 38(5): 762-768; doi: 10.1002/hed.23949.  (SCI)

Wang CC, Liu SA, Wu SH, Wang CP, Liang KL, Jiang RS, Lin JC. Transoral robotic surgery for early T classification hypopharyngeal cancer. Head Neck 2016 Jun;38(6):857-62. (SCI)

Wang CC, Liu SA, Wu SH, Lin WJ, Jiang RS, Wang L. Transoral robotic surgery for early glottic carcinoma involving anterior commissure: Preliminary reports. Head Neck. 2016 Jun;38(6):913-8. (SCI)

Chiang CY, Liu SA, Sheu ML, Chen FC, Chen CJ, Su HL, Pan HC. Feasibility of Human Amniotic Fluid Derived Stem Cells in Alleviation of Neuropathic Pain in Chronic Constrictive Injury Nerve Model. PLoS One 2016 Jul 21;11(7):e0159482. doi: 10.1371/journal.pone.0159482. (SCI)

Lin JC, Wang CC, Jiang RS, Wang WY, Liu SA*. Impact of microsatellite alteration in surgical margins on local recurrence in oral cavity cancer patients. Eur Arch Otorhinolaryngol 2017 Jan;274(1):431-439. doi: 10.1007/s00405-016-4215-y. (SCI)

Tsai YC, Liu SA, Lai CS, Chen YW, Lu CT, Yen JH, Chen IC. Functional Outcomes and Complications of Robot-Assisted Free Flap Oropharyngeal Reconstruction. Ann Plast Surg. 2017 Mar;78(3 Suppl 2):S76-S82. doi: 10.1097/SAP.0000000000001010.  (SCI)

Lin WJ, Wang CC, Jiang RS, Huang YC, Ho HC, Liu SA*. A prospective randomized study of LigaSure Small Jaw® versus conventional neck dissection in head and neck cancer patients. Clin Otolaryngol. 2017; 42(2):245-251. doi: 10.1111/coa.12702. (SCI)

Tsai WC, Kung PT, Huang KW, Wang YH, Liu SA*. Influence of time interval from diagnosis to treatment on survival for oral cavity cancer: A nationwide cohort study. PLoS One 2017 Apr 7;12(4):e0175148. doi: 10.1371/journal.pone.0175148 (SCI)

Liu SA*, Wang CC, Jiang RS, Lee FY, Lin WJ, Lin JC. Pathological features and their prognostic impacts on oral cavity cancer patients among different subsites – A single institute’s experience in Taiwan. Scientific Reports (UK) 2017; 7: 7451; doi: 10.1038/s41598-017-08022-w (SCI)

Pan SY, Liu SA, Sun MH, Tsou HK, Lee SD, Chen YJ, Sheehan J, Sheu ML, Pan HC. Outcome of hearing preservation related to tumor morphologic analysis in acoustic neuromas treated by gamma knife radiosurgery. Radiat Oncol 2017 Aug 15;12(1):134. doi: 10.1186/s13014-017-0875-z. (SCI)

Liu SA*, Wang CC, Jiang RS, Wang WY, Lin JC. Genetic analysis of surgical margins in oral cavity cancer. Br J Surg 2018;105:e142-e149 (SCI)

專書或專書論文:

耳鼻喉健康學習力UP 幼獅文化出版 (2010.09)

Liu SA. A Literature Analysis of the Risk Factors for Oral Cancer. In Ogbureke KUE, Editor. Oral Cancer (ISBN 978-953-51-0228-1). InTech — Open Access Company; 2012. p 65-77.

Liu SA. A Literature Analysis of the Prognostic Factors for Oral Cancer Patients. In Sheng-Po Hao, Editor. Oral Cancer: Symptoms, Management and Risk Factors" (ISBN: 978-1-62948-215-6). Nova Science Publishers, Inc.; 2013. p 77-105.