跳到主要內容區塊
Facebook
:::生殖醫學中心 > 公開資訊 > 學術論文

學術論文

引用 (4)
轉寄
列印
最後更新時間:2018/10/6 15:06:42
點閱:295

本中心歷年發表文獻

一.研究論文列表

1.人工生殖相關研究報告:

(1)試管嬰兒治療中,促性腺激素賀 爾蒙作用劑 (柳普林)在引卵過程的臨床經驗:短療程之優點

Chen MJ, Ho ESC, Chen JS, Chiue FL: Experience of GnRH agonist Leuprorelin in Ovulation Induction for In Vitro Fertilization: Benefits from a Short Course Regimen. J of Obstet & Gynecol, R.O.C. 30:130-135, 1991

(2)未受精的人類卵子細胞之染色體分析

Chen JS, Chen MJ, Guu HF, Lo FJ, Ho ESC: Chromosomal Analysis of Unfertilized Human Oocytes in IVF. J of Obstet & Gynecol, R.O.C. 30:241-245, 1991

(3)卵巢早衰病患接受卵子捐贈與試管嬰兒治療,成功三胞胎妊娠之個案報告與文獻回顧 

Chen MJ, Chiue FL, Ho ESC: Triplet Pregnancy in Premature Ovarian Failure After Oocyte Donation and In Vitro Fertilization: A Case Report and Review of Literature. Chinese Medical Journal (Taipei) 51:304-8,1993

(4)以人類壺腹細胞共同培養技術,對於精原蟲運動性的效應

Chen MJ, Chen JS, Guu HF, Ho ESC: The effect of the human ampullary cell coculture on the motility pattern of the human spermatozoa. J of Obstet Gynecol ROC 33(4):168-172, 1994

(5)黃體素與Dibutyryl cAMP對於引發人類精蟲頂體反應與臨床受精能力之比較

Chen JS, Guu HF, Chen MJ, Ho ESC: Different responsiveness to progesterone and Dibutyryl cAMP of human sperm to trigger acrosome reaction and clinical fertilizing ability. J of Obstet Gynecol ROC 33(3):107-114, 1994

(6)以雙重標定FISH法,評估精原蟲-白蛋白性別篩選分離技術之成效

Chen MJ, Guu HF, Ho ESC. Efficiency of sex-preselection of spermatozoa by albumin separation method evaluated by double-labelled fluorescence in situ hybridization. Hum Reprod 12 (9): 1920-1926, 1997 

該文章明白指出臨床上使用之白蛋白精子分離術對於精子性別篩選之謬誤,使社會大眾明瞭其中之奧密,意在導正醫界及社會對於非醫學理由篩選胎兒性別之不當作法。〔目前被引用13次〕

(7)三種超快速胚胎冷凍技術之評估

Yih YC, Chen MJ*, Ho ESC. Comparative evaluation of three ultrarapid freezing protocols for cryopreservation of embryos. J Reprod Infertil 6(4): 134-140, 1997

(8)人工生殖時人類卵胞漿內精子注射術與蒼鼠卵卵胞漿內精子注射檢驗之相關性研究

He FF, Liow SL, Ng SC, Chen MJ. Correlation of intracytoplasmic sperm injection with hamster intracytoplasmic injection assay. J Reprod Med (Chinese) 7(4):207-211, 1998

(9)比較兩種不同精子密度梯度分離技術對於人工協助受孕之評估

Chen MJ, Bongso A. Comparative evaluation of two density gradient preparations for sperm separation for medically assisted conception. Hum Reprod 14(3): 759-764, 1999

    該文章探討試管嬰兒治療時之精子備製方法,對於如何使用密度梯度離心分離法有最根本之方法分析,對提昇臨床人工生殖之成果頗有貢獻。〔目前被引用73次〕

(10)精子密度梯度分離術於人工協助受孕中所扮演的角色

Chen MJ*: The role of density gradients in medically assisted conception. J Reprod Infertil (1): 12-29, 1999

(11)體外大鼠卵子自動活化的模式

He FF, Liow SL, Chen MJ, Ng SC, Qe QS. Spontaneous activation of hamster oocytes in vitro. Chinese Medical Journal 112(12):1105-1108, 1999 

(12)試管嬰兒與精子顯微注射療程中,卵子培養前期的長短對於細胞核成熟、受精率、受精卵品質與懷孕成果的評估

Ho JY (何彥秉), Chen MJ (陳明哲), YiYC (易瑜嶠), Guu HF, Ho ES (何師竹). (2003/09) The effect of preincubation period of oocytes on nuclear maturity, fertilization rate, embryo quality, and pregnancy outcome in IVF and ICSI. J Assist Reprod Genet 2003;20:357-363. (SCI)

(13)濾泡期晚期,造成濾泡成長停滯的LH極限值

H o JY (何彥秉), Hwang JL, Chen MJ (陳明哲), Guu HF, Ho ES (何師竹). (2004/02) What is the LH ceiling level for follicular growth arrest in late follicular phase? Hum Reprod. 2004;19:463-464. (SCI)

 

(14)低劑量柳普林在長療程試管嬰兒治療中,對卵巢反應與週期結果之影響

Yi YC, Chen MJ*, Ku HF, Ho ES, Effects of a low-dose leuprorelin long protocol on the ovarian response and cycle outcome in IVF. Taiwanese J Obstet Gynecol. 43:97-100, 2004.

(15)腦下垂體下調作用病人於開始引卵藥物前的血清FSH/LH比值,反比於成熟取卵數目,並可用於反應低下之預估

Ho JY (何彥秉), Guu HF, Yi YC (易瑜嶠), Chen MJ (陳明哲), Ho ES (何師竹). (2005/04) The serum follicle-stimulting hormone-to-luteinizing hormone ratio at the start of stimulation with gonadotropins after pituitary down-regulation is inversely correlated with a mature oocyte yield and can predict "low responders". Fertil Steril. 2005;83:883-888. (SCI)

(16)對於人工生殖中粒腺體扮演的角色以動物實驗提供確切的證據

Yu-Chiao Yi , Ming-Jer Chen , Jason Yen-Ping Ho,Hwa-Fen Guu , Esther Shih-Chu Ho. Mitochondria transfer can enhance the murine embryo development. Assist Reprod Genet (2007) 24:445–449 (SCI)

(17)人工生殖週期中當發生提前黃體化時,可以囊胚植入有效改善懷孕成效

Huang PC, Chen MJ, Guu HF, Yi YC, Ho JY, Chen YF, Chen LY and Chou MM. Is it possible to improve pregnancy outcomes by shifting to blastocyst transfer in ART cycles with premature serum progesterone rise? Taiwan J Obstet gynecol. (In pressed)

2.懷孕相關研究報告

(1)以經陰道超音波M-mode評估早期懷孕之胎兒心律活動,及其與胎兒頭臀徑 (CRL)之相關性

Ho ESC, Chen MJ, Lee YH: Transvaginal M-mode Sonographic Documentation of Cardiac activity in Very Early Pregnancy and Its Correlation with Crown Rump Length. J of Ultrasound in Medicine, R.O.C. 6:116, 1989

(2)先天性處女膜閉鎖次發胎兒子宮腔水腫之產前診斷個案報告

 Tseng JJ (曾振志), Ho JY (何彥秉), Chen WH (陳文賢), Chou MM (周明明). (2008/06) Prenatal diagnosis of isolated fetal hydrocolpos secondary to congenital imperforate hymen. J Chin Med Assoc 2008; 71:325-328. (SCI)

(3)藥物治療無效之產後大出血子宮,於血管栓塞後發生急性續膿性子宮肌肉發炎、併發子宮壞死之個案報告。

Tseng JJ (曾振志), Ho JY (何彥秉), Hwang JI. Uterine necrosis associated with acute suppurative myometritis after angiographic selective embolization for refractory postpartum hemorrhage. Am J Obstet Gynecol. 2011 Jun;204(6):e4-6. (SCI)

3.治療內膜異位症之相關研究報告

(1)嚴重內膜異位症病人反覆治療失敗後,結合單一次開腹手術與試管嬰兒治療成功懷孕之個案報告

Tseng CR, Chen MJ, Ou-Yang XR. Pregnancy after Combined IVF and Surgery at a Single Laparotomy in a Patient with Severe Endomeriosis Who Failed Four Previous Attempts.    J Reprod Infertil 1:87-90, 1992

(2)以腹腔鏡手術治療內膜異位瘤之台中榮總前趨性報告

Chen MJ, Ho ESC, Chen JS, Soong GSM: Laparoscopic Management of Endometriosis with Endometrioma – A Preliminary report from Taichung VGH. J Reprod Infertil 2:45-50, 1993

(3)以腹腔鏡手術治療合併有中/重度內膜異位症之不孕症患者

Chen JS, Chen MJ, Ho ESC. Laparoscopic management of moderate/severe endometriosis with infertility. J of Obstet Gynecol ROC 34(1): 21-25, 1995

(4)柳普林用於治療子宮內膜異位症之臨床經驗

Chen MJ, Hwang WR, Ho ESC. Clinical Experiences of the Leuplin Depot in the Management of Patients with endometriosis. J of Obstet Gynecol ROC 35(2): 91-99, 1996

(5)對於子宮內膜異位提供全新的診斷工具

Yi, Yu-Chiao,Wang, Shih-Chi,hao, Chun-Chin,Su, Chia-Ling,Lee, Yao-Ling,Chen, Ling-Yun.Evaluation  Serum Autoantibody Levels in the Diagnosis of Ovarian Endometrioma.J Clin Lab Anal. 2010;24(5):357-62.(SCI)

4.手術之相關

(1)腹腔鏡影像系統對於良性骨盆腔疾病之運用

Ho ESC, Chen JS, Chen MJ: Video pelviscopy in Benign Pelvic Diseases. J of Obstet & Gynecol, R.O.C. 31:39-43, 1992

(2)腹腔鏡手術治療卵巢良性畸胎瘤

Chen JS, Ho ESC, Chen MJ: Operative Laparoscopy in Benign Cystic Teratoma of Ovary. Chinese Medical Journal (Taipei) 50:194-7,1992

(3)腹腔鏡子宮切除與傳統開腹或經陰道子宮切除手術之比較

Chen MJ, Chen JS, Liu KC, Ho ESC. Is laparoscopic hysterectomy and laparoscopically assited vaginal hysterectomy worth while? comparison with abdominal and vaginal hysterectomy. J of Obstet Gynecol ROC 34(1): 45-50, 1995

(4)健康停經後婦女使用口服合成雌激素與經皮雌激素貼片,其在動脈硬化危險因子與血管內膜功能的個別成效

 Ho JY (何彥秉), Chen MJ (陳明哲), Sheu WH (許惠恒), Yi YC (易瑜嶠), Tsai AC, Guu HF, Ho ES (何師竹). (2006/10) Differential effects of oral conjugated equine estrogen and transdermal estrogen on atherosclerotic vascular disease risk markers and endothelial function in healthy postmenopausal women. Hum Reprod. 2006;21:2715-2720. (SCI)

(5)單一階段子宮鏡成功移除巨大黏膜下肌瘤

Kang FW, Yang HC, Chen MJ, Chou MM, Ho ES. One step hysteroscopic removal of large sinking submucous myoma. Taiwan J Obstet gynecol. 2008 Jun; 47(2): 238-40.

(6)LOX類似蛋白1、α1-抗胰蛋白?及嗜中性彈性蛋白?在骨盆腔器官脫垂病人的特殊表現

Man WC, Ho JY, Wen Y, Sokol ER, Polan ML, Chen B. (2009/12) Is lysyl oxidase-like protein-1, alpha-1 antitrypsin, and neutrophil elastase site specific in pelvic organ prolapse? Int Urogynecol J Pelvic Floor Dysfunct. 2009 Dec;20(12):1423-9. (SCI)

(7)TIMP-1 基因多型性與子宮內膜癌的相關性

Yi, Yu-Chiao,Chen, Mu-Kuan,Chen, Ling-Yun,Ho, Esther Shih-Chu,Ying, n Tsung-Ho,Wang, Po-Hui,Yang, Shun-Fa. Genetic polymorphism of the tissue inhibitor of metalloproteinase-1 is associated with an increased risk of endometrial cancer. Clin Chim Acta. 2009 ;409(1-2):127-31.(SCI)

(8)紐西蘭白兔胚胎幹細胞株之特性

Intawicha P, Ou YW, Lo NW, Zhang SC, Chen YZ, Lin TA, Su HL, Guu HF, Chen MJ, Lee KS, Chiu YT, Ju JC. Characterization of embryonic stem cell lines derived from New Zealand white rabbit embryos. Cloning and Stem cells 2009; 11:1-11(SCI)

(9)對於MMP-7在子宮內膜癌的發生中所扮演的角色提出臨床上的證據Yu-ChiaoYi, Pai-Ta Chou,Ling-Yun Chen,Wu-Hsien Kuo, Esther Shih-Chu Ho,

Chih-Ping Han, Shun-Fa Yang. Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility. Clin Chem Lab Med. 2010 ;48(3):337-44;(SCI)

(8)生殖泌尿道脫垂個案,其陰道上皮自殺因子之表現

Wen Y, Ho JY (何彥秉), Polan ML, Chen B. Expression of apoptotic factors in vaginal tissues from women with urogenital prolapse. Neurourol Urodyn. 2011 Nov;30(8):1627-32. (SCI)

(9)轉化生長因子在子宮肌瘤的表現

Ho JY, Man WC, Wen Y, Polan ML, Ho ES (何師竹), Chen B. (2010/08) Transforming growth interacting factor expression in leiomyoma compared with myometrium. Fertil Steril. 2010 Aug;94(3):1078-83. (SCI)

(10)子宮肌瘤切除切除與非子宮肌瘤手術病人,在子宮動脈阻斷術後,生殖與懷孕結果之比較

Chang KM, Chen MJ, Lee MH, Huang YD, Chen CS. Fertility and pregnancy outcomes after uterine artery occlusion with or without myomectomy. Taiwan J Obstet gynecol. 2012 Sep; 51(3): 331-335 (SCI).

二.研討會論文列表

1.    Chen MJ, Guu HF, Yi YC, Chen YF, Ho YP, Huang PC, Chen LY, Chou MM  Advanced sperm selection, does it help? 2013 Taiwanese Society of Reproductive Medicine (Prize poster)

   2013年台灣生殖醫學會年會海報論文獎首獎

   探討高階精子挑選術對人工生殖之貢獻

2.    Chen MJ, Chen YF, Guu HF, Yi YC, Ho YP, Huang PC, Chen LY, Chou MM. Clinical validation of sperm morphology by Kruger’s strict criteria in ART treatment. 2013 Taiwanese Society of Reproductive Medicine

3.   Chen MJ, Guu HF, Chen YF, Yi YC, Ho YP, Lin TI, Chen LY, Chou MM. Is it possible to rescue the lowered pregnancy rates by shifting to D5 embryo transfer in cycles of prematurely elevated serum progesterone level? 2012 Taiwanese Society of Reproductive Medicine

4.   Chen MJ, Chen YF, Guu HF, Yi YC, Ho YP, Lin TI, Chen LY, Chou MM.To transfer or to freeze, how could we choose? 2012 Taiwanese Society of Reproductive Medicine

5.    Chen MJ, Guu HF, Chen YF, Yi YC, Ho YP, Lin TI, Chen LY, Ho SC.Would assisted hatching help ART patients younger than age 38? 2011 Taiwanese Society of Reproductive Medicine

6.   Chen MJ, Guu HF, Chen YF, Yi YC, Ho YP, Lin TI, Chen LY, Ho SC.ICSI may improve embryo quality in non-male factor infertility patients with suboptimal fertilizations but not in those with normal fertilization by IVF treatment. 2010 Taiwanese Society of Reproductive Medicine

7.    Chen MJ*, Chen YF, Guu HF, Yi YC, Ho, JY, Lin TI, Chen LY, Ho ESC. ICSI improves embryo quality in non-male factor patients with subnormal fertilization but not in those with normal fertilization by IVF treatment. 2010 ESHRE meeting June 28, Rome, Italy

Chen MJ*, Chen YF, Guu HF, Yi YC, Ho, JY, Lin TI, Chen LY, Ho ESC.

1.    Does luteal phase Decapeptyl supplement improve ART outcome?  2009 Aug. Pacific Rim Society of Fertility and Sterility and Taiwanese society of Reproductive Medicine.(Prize paper)                                            2009年環太平洋岸生育及絕育醫學會暨台灣生殖醫學會年會口頭論文獎首獎:探討如何改善人工生殖之黃體期補充方式以提高懷孕成功率

9.    Yi YC, Chen MJ*, Guu HF, Chen YF, Ho JYP, Lin TI. Impact of Semen parameters on intacytoplasmic sperm injection outcomes. 2009 Aug. Pacific Rim Society of Fertility and Sterility

10.    陳明哲* 谷化芬 陳雅芳易瑜嶠 何彥秉 林宗毅 陳麗宇Dosing adjustment for COH, does it benefit the repeated ART cycles? 2008 Taiwanese Society of Reproductive Medicine.

11.    陳明哲* 谷化芬 易瑜嶠何彥秉 林宗毅 陳雅芳 陳麗宇 何師竹GnRH-agonist or GnRH-antagonist, which is better? An analysis of the outcome by different GnRH analogue co-treatment for COH in our ART program. 2008 Taiwanese Association of Obsterics and Gynecology

12.    陳明哲*  林宗毅 易瑜嶠 何彥秉 谷化芬 陳雅芳 Should ovulation induction regimen for ART be altered after laparoscopic conservative surgeries for patients with moderate to severe endometriosis? 2007 Taiwanese Society of Reproductive Medicine

13.    陳明哲*  陳雅芳 谷化芬 易瑜嶠 何彥秉 林宗毅Impact of paternal age on the successful outcomes in an assisted reproduction program  2007 Taiwanese Society of Reproductive Medicine

14.    陳明哲* 谷化芬 易瑜嶠何彥秉 林宗毅 陳雅芳 何師竹. Insight into the impact of dominant follicular size in Cetrotide cycles on the pregnancy and delivery outcome in an IVF/ICSI program 2007 Taiwanese Association of Obsterics and Gynecology

15.    何彥秉 周寬基* 陳明哲 蔡啟瑋姜淑芬* 谷化芬Microarray analysis of the expression profiles of granulosa cells from large and small ovarian follicles 2006 Taiwanese Society of Reproductive Medicine